Of uncertain affinity; {lonesome} that {is} (by implication) waste (usually as a {noun} G5561 being implied): - {desert} {desolate} {solitary} wilderness.
Mat 12:25And Jesus knew their thoughts, and said unto them, Every kingdom divided against itself is brought to desolationG2049; and every city or house divided against itself shall not stand:
Luk 11:17But he, knowing their thoughts, said unto them, Every kingdom divided against itself is brought to desolationG2049; and a house divided against a house falleth.
Rev 17:16And the ten horns which thou sawest upon the beast, these shall hate the whore, and shall make her desolateG2049 and naked, and shall eat her flesh, and burn her with fire.
Rev 18:17For in one hour so great riches is come to noughtG2049. And every shipmaster, and all the company in ships, and sailors, and as many as trade by sea, stood afar off,
Rev 18:19And they cast dust on their heads, and cried, weeping and wailing, saying, Alas, alas, that great city, wherein were made rich all that had ships in the sea by reason of her costliness! for in one hour is she made desolateG2049.